Specifications subject to changewithout notice
PRPCentrifuge
Vibrationfreecentrifugationwithrightspeed,time&temperature is importantfor intactbiologicalproperties
Platelet’sProcessing&storingtemperatureat22*C is important
.................................................
*AABBTechnicalManual18thEdition
Coolingcentrifugesavesplateletsfromtheeffectofheatgeneratedduringcentrifugation
.........
**BloodVol32,No.2(August),1998
Autologous Platelets: Effective but Delicate toHandle
PRP - Platelet Rich Plasma
ThePRP therapy is gaining inpopularityas single supportive treatment option formany indications. Autologous PRP contains different growth
factors and other cytokines whichmay elicit gathering of stem cells around the damaged region stimulating cellular proliferation and tissue
regeneration.
PRPcontainsgrowthfactorsthatstimulatecellulargrowthanddivision.
TGF-B(TransformingGrowthFactor-beta)
bGFG(BasicFibroblastGrowthFactor)
PDGFa-b(PlateletDerivedGrowthFactor)
EGF(EpidermalGrowthFactor)
VEGF(VascularEndothelialGrowthFactor)
CTGF(ConnectiveTissueGrowthFactor)
Keep blood at room temperature
(20 to 24 C) before separating
platelet-rich plasma from the red
cells. This separation must take
place wi thin 8 hours of
phlebotomy.
* Method6.13. Preparationof
Platelets fromWholeBlood
; AABB
TechnicalManual 18thEdition
Heat induced loss of functional
capacity is due to irreversible
structural changes in platelets
developafterwarmingPRPabove
0
40 C. Heat produced a distinct
morphological transformation
characterized by loss of discoid
shape, irregular swelling, and
movement of hyaloplasmic
organelles.
**Effect of heat onplatelet structure
and function
; Dr JamesG.White;
Blood, Vol.32, No. 2 (August), 1998
Advantage
PRP
Effective
Because the treatment
uses growth factors, its
effects are superior &
effective.
Natural
Patient feel nosenseof
violation by foreign
bod i es and t he
treatment effects are
completelynatural.
Convenient
The treatment is quick
and absolutely non-
Invasive.
Safe
Usingautologousblood
means there is no risk
of infection, allergic
reaction, or any other
sideeffect.
